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Effects of teriparatide versus risedronate following pertrochanteric fracture fixation

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Ace Report Cover
October 2017

Effects of teriparatide versus risedronate following pertrochanteric fracture fixation

Vol: 6| Issue: 10| Number:19| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:2

Effects of Teriparatide Compared with Risedronate on Recovery After Pertrochanteric Hip Fracture: Results of a Randomized, Active-Controlled, Double-Blind Clinical Trial at 26 Weeks

J Bone Joint Surg Am. 2016 Nov 16;98(22):1868-1878

Contributing Authors:
S Overgaard F Frihagen P Aspenberg F Marin H Petto J Malouf U Tarantino PA García-Hernández C Corradini JJ Stepan L Borris E Lespessailles K Papavasiliou JR Caeiro

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Synopsis

224 patients over the age of 50 with a pertrochanteric hip fracture who had undergone fixation were randomized to 26 weeks of daily subcutaneous teriparatide 20ug or weekly oral risedronate 35mg. The purpose of this study was to compare measures of functional and clinical outcome, as well as safety outcomes and fracture healing over a 26-week follow-up. Results demonstrated significantly better Ti...

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