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Meta-analysis
ACE Report #9146
Ace Report Cover Osteoarthritis

Platelet-rich plasma improves WOMAC scores compared to hyaluronic acid in knee OA


Study Type:Meta-analysis/Systematic Review
OE Level Evidence:1
Journal Level of Evidence:N/A

Efficacy of Platelet-Rich Plasma versus Hyaluronic Acid for treatment of Knee Osteoarthritis: A systematic review and meta-analysis.

Electron Physician. 2016 Mar 25;8(3):2115-22. doi: 10.19082/2115. eCollection 2016.

Contributing Authors: HN Sadabad M Behzadifar F Arasteh HR Dehghan

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Synopsis

6 randomized clinical trials were included in this meta-analysis to evaluate the comparative efficacy of platelet-rich plasma (PRP) and hyaluronic acid (HA) in the management of knee osteoarthritis. The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) was used to evaluate outcome. The results of this meta-analysis demonstrated low-quality evidence that PRP provided favourable...

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