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Meta-analysis
ACE Report #9097
Ace Report Cover Osteoarthritis

Oral NSAIDs versus opioids for pain management of patients with knee OA


Study Type:Meta-analysis/Systematic Review
OE Level Evidence:N/A
Journal Level of Evidence:N/A

Comparative pain reduction of oral non-steroidal anti-inflammatory drugs and opioids for knee osteoarthritis: systematic analytic review

Osteoarthritis Cartilage. 2016 Jun;24(6):962-72

Contributing Authors: E Losina J Katz JE Collins Bhushan R Deshpande

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Synopsis

17 randomized controlled trials were included in this systematic analytic review and meta-analysis to determine the comparative efficacy of oral non-steroidal anti-inflammatory drugs (NSAIDs) and opioids in the management of pain for patients with knee osteoarthritis (OA). Interventions included NSAIDs only (n=11 studies), less potent opioids (n=3 studies), both NSAIDs and less potent opioids (n=1...

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