The efficacy & safety of various doses of fulranumab vs placebo for chronic LBP
Efficacy, Safety, and Tolerability of Fulranumab as an Adjunctive Therapy in Patients With Inadequately Controlled, Moderate-to-Severe Chronic Low Back Pain: A Randomized, Double-blind, Placebo-controlled, Dose-ranging, Dose-loading Phase II StudyClin Ther. 2016 Jun;38(6):1435-50
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389 patients with moderate-to-severe chronic low back pain (LBP) were randomized to receive one of five dose-ranging subcutaneous injection treatments: 1mg fulranumab every 4 weeks, 3mg fulranumab every 4 weeks, 3mg fulranumab every 4 weeks after a 6mg loading dose, 10mg fulranumab every 4 weeks, or placebo every 4 weeks. The purpose of this study was to determine the efficacy and safety of fulran...
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