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Lower blood loss with IV+IA TXA versus IV TXA alone following total knee arthroplasty
August 2016
Lower blood loss with IV+IA TXA versus IV TXA alone following total knee arthroplasty
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Combined Intra-Articular and Intravenous Tranexamic Acid Reduces Blood Loss in Total Knee Arthroplasty: A Randomized, Double-Blind, Placebo-Controlled Trial
J Bone Joint Surg Am. 2016 May 18;98(10):835-41Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
60 patients scheduled for unilateral total knee arthroplasty were randomized to either combined intravenous and intra-articular tranexamic acid administration, or intravenous TXA administration alone. The purpose of this study was to determine if combined IV-IA TXA administration offered lower 24-hour blood loss compared to IV administration alone. In addition to significantly lower 24-hr blood lo...
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