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RCT
ACE Report #9026
Ace Report Cover General Orthopaedics

Hydroxyapatite + collagen vs. beta-tricalcium phosphate in bone substitution implantation


Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Efficacy and safety of porous hydroxyapatite/type 1 collagen composite implantation for bone regeneration: A randomized controlled study

J Orthop Sci. 2016 May;21(3):373-80.

Contributing Authors: S Sotome K Ae A Okawa M Ishizuki H Morioka S Matsumoto T Nakamura S Abe Y Beppu K Shinomiya

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Synopsis

130 patients undergoing bone substitution implantation were randomized to one of two synthetic porous composite groups for the purpose of comparing the efficacy and safety throughout a 24-week period: (1) porous hydroxyapatite/collagen composite (HAp/CoL) or (2) porous beta-tricalcium phosphate (beta-TCP). Results demonstrated that a significantly larger proportion of patients in the HAp/CoL had "...

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