ACE Report #8836
Ace Report Cover Trauma

OARSI 2016: Allogenic mesenchymal precursor cells + hyaluronan injection after ACL repair

Study Type:Therapy
OE Level Evidence:N/A
Journal Level of Evidence:N/A

Randomized double-blind study of a single intra-articular injection of allogeneic mesenchymal precursor cells + hyaluronan compared to hyaluronan alone to explore clinical and structural outcomes in patients post anterior cruciate ligament reconstruction

Contributing Authors: F Cicuttini Y Wang P Marks J Linklater D Connell S Hall P Ghosh D Skerrett S Itescu A Shimmin

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This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.


17 patients with an anterior cruciate ligament injury undergoing surgical reconstruction were randomized to receive a singular intraarticular injection of hyaluronan (HA) with or without allogeneic STRO-1+ human mesenchymal precursor cells (MPC). The purpose of this study was to determine if the administration of allogeneic immunodeficient STRO-1+ human MPC resulted in significantly improved clini...

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