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Addition of epinephrine toTXA, and the effect on perioperative blood loss in THA

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Ace Report Cover
June 2016

Addition of epinephrine toTXA, and the effect on perioperative blood loss in THA

Vol: 5| Issue: 6| Number:34| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

A randomized trial of the effect of low dose epinephrine infusion in addition to tranexamic acid on blood loss during total hip arthroplasty

Br J Anaesth. 2016 Mar;116(3):357-62

Contributing Authors:
Ø Jans U Grevstad H Mandøe H Kehlet PI Johansson

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Synopsis

106 patients scheduled for total hip arthroplasty were randomized to management with either the combination of low-dose epinephrine infusion and intravenous tranexamic acid, or tranexamic acid alone. The purpose of this study was to evaluate whether additional intravenous epinephrine administration significantly reduced intraoperative blood loss and total blood loss over the first 24 hours postope...

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