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RCT
ACE Report #8778
Ace Report Cover Osteoarthritis

Both PRP and HA injections improve pain and function in early knee OA compared to saline


Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Multiple PRP injections are more effective than single injections and hyaluronic acid in knees with early osteoarthritis: a randomized, double-blind, placebo-controlled trial

Knee Surg Sports Traumatol Arthrosc. 2017 Mar;25(3):958-965

Contributing Authors: G Görmeli CA Görmeli B Ataoglu C Çolak O Aslantürk K Ertem

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Synopsis

182 patients with knee osteoarthritis (OA) were randomized to one of four groups: PRP-3 (3 injections), PRP-1 (single injection), hyaluronic acid (HA), or saline injections. All active treatment groups (PRP-3, PRP-1, HA) demonstrated significantly more favourable EQ-VAS pain scores and IKDC scores compared to saline injections.The patients treated with three injections of platelet-rich plasma (PRP...

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