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No clinically important effects of hyaluronic acid injection in knee osteoarthritis
January 2016
No clinically important effects of hyaluronic acid injection in knee osteoarthritis
Study Type:Meta-analysis/Systematic Review
OE Level Evidence:2
Journal Level of Evidence:1
Viscosupplementation for Osteoarthritis of the Knee: A Systematic Review of the Evidence
J Bone Joint Surg Am. 2015 Dec 16;97(24):2047-60Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
19 randomized controlled trials (4485 patients) analyzing the effects of hyaluronic acid injection on pain, function and stiffness in knee osteoarthritis patients were included. The purpose of this meta-analysis was to determine the clinical significance of hyaluronic acid and which trial factors influence the treatment effects on pain, function, and stiffness. The results displayed that double-bl...
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