No clinically important effects of hyaluronic acid injection in knee osteoarthritis
Viscosupplementation for Osteoarthritis of the Knee: A Systematic Review of the EvidenceJ Bone Joint Surg Am. 2015 Dec 16;97(24):2047-60
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19 randomized controlled trials (4485 patients) analyzing the effects of hyaluronic acid injection on pain, function and stiffness in knee osteoarthritis patients were included. The purpose of this meta-analysis was to determine the clinical significance of hyaluronic acid and which trial factors influence the treatment effects on pain, function, and stiffness. The results displayed that double-bl...
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