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Volume:5 Issue:1 Number:61 ISSN#:2563-5476
Author Verified
ACE Report #8430
Ace Report Cover Osteoarthritis

No clinically important effects of hyaluronic acid injection in knee osteoarthritis

How to Cite

OrthoEvidence. No clinically important effects of hyaluronic acid injection in knee osteoarthritis. ACE Report. 2016;5(1):61. Available from: https://myorthoevidene.com/AceReport/Report/8430

Study Type:Meta-analysis/Systematic Review
OE Level Evidence:2
Journal Level of Evidence:1

Viscosupplementation for Osteoarthritis of the Knee: A Systematic Review of the Evidence

J Bone Joint Surg Am. 2015 Dec 16;97(24):2047-60

Contributing Authors: D Jevsevar P Donnelly GA Brown DS Cummins

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19 randomized controlled trials (4485 patients) analyzing the effects of hyaluronic acid injection on pain, function and stiffness in knee osteoarthritis patients were included. The purpose of this meta-analysis was to determine the clinical significance of hyaluronic acid and which trial factors influence the treatment effects on pain, function, and stiffness. The results displayed that double-bl...

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