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ACE Report #8429
Ace Report Cover Osteoarthritis

Differences in hyaluronic acid characteristics influence outcomes in knee OA patients

Study Type:Meta analysis
OE Level Evidence:2
Journal Level of Evidence:N/A

Product Differences in Intra-articular Hyaluronic Acids for Osteoarthritis of the Knee

Am J Sports Med. 2016 Aug;44(8):2158-65

Contributing Authors: RD Altman A Bedi J Karlsson P Sancheti E Schemitsch

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68 randomized controlled studies evaluating the effects of intra-articular hyaluronic acid injections in patients with knee osteoarthritis were selected for inclusion. The purpose of this meta-analysis was to compare the safety and efficacy of differing hyaluronic acid preparations for the treatment of knee osteoarthritis. The results displayed the greatest pain efficacy in high-molecular-weight h...

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