Visit our Evidence-Based Covid-19 Website and Stay Up to Date with the latest Research.
ACE Report #8340
Ace Report Cover Osteoarthritis

Efficacy of hyaluronic acid for pain reduction in knee OA versus control arthrocentesis

Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Clinical effects of intraarticular injection of high molecular weight hyaluronan (Orthovisc) in osteoarthritis of the knee: a randomized, controlled, multicenter trial

J Rheumatol. 2005 Oct;32(10):1928-36

Contributing Authors: D Neustadt J Caldwell M Bell J Wade J Gimbel

Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here


372 patients with Kellgren-Lawrence grade I-III knee osteoarthritis (OA) were randomized to either four intra-articular injections of high-molecular-weight (HMW) hyaluronic acid (HA), three intra-articular injections of HMW HA and one control arthrocentesis, or four sessions of control arthrocentesis. The primary outcome was the percentage of patients demonstrating a minimum 20% relative reduction...

CME Image

Continuing Medical Education Credits

You could be earning 0.5 CME credits for each report you read.


Please Login or Join to leave comments.