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RCT
ACE Report #8176
Ace Report Cover Osteoarthritis

Clinical benefit of Hylan GF-20 over conventional therapy at similar cost in knee OA


Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Prospective randomized study comparing the medicoeconomic benefits of Hylan GF-20 vs. conventional treatment in knee osteoarthritis

Joint Bone Spine. 2003 Aug;70(4):276-81

Contributing Authors: A Kahan PL Lleu L Salin

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Synopsis

506 patients with knee osteoarthritis and failed response to pharmacological intervention were randomized to receive either three weekly intra-articular injections of Hylan G-F 20 (Synvisc) or conventional therapy. The purpose of the study was to compare the clinical efficacy of the two treatment regimens over a span of 9 months, as well as to evaluate economic factors associated with Hylan G-F 20...

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