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Hyaluronic acid injections reduce IL-1B and severity of knee OA after 5 weeks
January 2016
Hyaluronic acid injections reduce IL-1B and severity of knee OA after 5 weeks
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
The effect of sodium hyaluronate treating knee osteoarthritis on synovial fluid interleukin -1β and clinical treatment mechanism
Pak J Pharm Sci. 2015 Jan;28(1 Suppl):407-10.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
40 patients with osteoarthritis of the knee were randomized to receive either intra-articular hyaluronic acid injections or placebo injections weekly, for 5 weeks. The purpose of the study was to compare the interleukin-1B content of the knee joint synovial fluid and the severity of knee osteoarthritis in these patients and with a healthy control group, before and after treatment. The results indi...
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