Intra-articular high-molecular weight HA injections similar to placebo in knee OA
Intra-articular hyaluronan injections for the treatment of osteoarthritis of the knee: a randomized, double blind, placebo controlled studyClin Exp Rheumatol. 2001 May-Jun;19(3):265-70
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49 patients with osteoarthritis of the knee were randomized to receive either a placebo or a high-molecular weight hyaluronic acid preparation administered through an intra-articular injection, weekly for 5 weeks. The purpose of the study was to determine how tolerable and effective this hyaluronic acid preparation (BioHy) was over a period of 5 weeks in comparison to a placebo regimen. The result...
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