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Hyaluronic acid injection similar in symptom & structure of knee OA vs diacerein & placebo
January 2016
Hyaluronic acid injection similar in symptom & structure of knee OA vs diacerein & placebo
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Evaluation of the symptomatic and structural efficacy of a new hyaluronic acid compound, NRD101, in comparison with diacerein and placebo in a 1 year randomised controlled study in symptomatic knee osteoarthritis
Ann Rheum Dis. 2004 Dec;63(12):1611-7Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
301 patients, over 50 years of age, with knee osteoarthritis, were randomized to receive either oral diacerein treatment (100mg/day) and 3 courses of intra-articular saline injections, oral placebo (100mg/day) and 3 courses of intra-articular saline injections, or oral placebo (100mg/day) and 3 courses of intra-articular hyaluronic acid injections (NRD101). The purpose of the study was to compare ...
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