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IA-hyaluronan injections and time-to-knee replacement in those with K-L grade IV knee OA
January 2016
IA-hyaluronan injections and time-to-knee replacement in those with K-L grade IV knee OA
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Intra-Articular Hyaluronan Treatment of Patients with Knee Osteoarthritis Waiting for Replacement Surgery
The Open Arthritis Journal, 2008, 1, 1-7Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
52 patients with grade IV knee osteoarthritis were randomly assigned to receive intra-articular injection of either hyaluronan (HA) or saline placebo. The purpose of this study was to determine if intra-articular HA, administered in two courses of 5 weekly injections, could delay the need for joint replacement surgery. Results demonstrated no significant difference in the time to joint replacemen...
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