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ACE Report #8130
Ace Report Cover Osteoarthritis

Efficacy and safety of a single, 6mL Hylan G-F 20 injection in knee OA treatment

Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Single, intra-articular treatment with 6 ml hylan G-F 20 in patients with symptomatic primary osteoarthritis of the knee: a randomised, multicentre, double-blind, placebo controlled trial

Ann Rheum Dis. 2010 Jan;69(1):113-9

Contributing Authors: X Chevalier J Jerosch P Goupille N van Dijk FP Luyten DL Scott F Bailleul K Pavelka

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253 patients with primary knee osteoarthritis (OA) were randomized to receive a single intra-articular injection of either 6mL Hylan G-F 20 or saline placebo. The purpose of the study was to assess the efficacy of Hylan G-F 20 at reducing pain and improving knee function, as well as to assess the safety of its use. The primary outcome of interest was pain at 26 weeks after injection, as measured b...

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