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Intraarticular TXA injection reduces blood loss & transfusion requirement in TKA at 5 days

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Ace Report Cover
November 2015

Intraarticular TXA injection reduces blood loss & transfusion requirement in TKA at 5 days

Vol: 4| Issue: 11| Number:34| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Safety and efficacy of intra-articular tranexamic acid injection without drainage on blood loss in total knee arthroplasty: A randomized clinical trial

Int J Surg. 2015 Aug;20:1-7.

Contributing Authors:
CG Wang ZH Sun J Liu JG Cao ZJ Li

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Synopsis

60 patients undergoing unilateral total knee arthroplasty were randomized to receive either an intra-articular tranexamic acid injection or a saline injection immediately after skin closure. The purpose of this study was to determine the safety and efficacy of tranexamic acid without drainage in these patients over 5 days after surgery. The results indicated a significant reduction in total blood ...

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