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Volume:2 Issue:7 Number:59 ISSN#:2563-5476
RCT
ACE Report #793
Ace Report Cover General Orthopaedics

Rheumatoid arthritis: Improvement in clinical outcome similar between 4 drug therapies


How to Cite

OrthoEvidence. Rheumatoid arthritis: Improvement in clinical outcome similar between 4 drug therapies. ACE Report. 2013;2(7):59. Available from: https://myorthoevidence.com/AceReport/Report/793

Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Comparison of Treatment Strategies in Early Rheumatoid Arthritis: A Randomized Trial

Ann Intern Med. 2007 Mar 20;146(6):406-15

Contributing Authors: YP Goekoop-Ruiterman JK de Vries-Bouwstra CF Allaart D van Zeben PJ Kerstens JM Hazes AH Zwinderman AJ Peeters JM de Jonge-Bok C Mallée WM de Beus PB de Sonnaville JA Ewals FC Breedveld BA Dijkmans

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Synopsis

508 patients with early rheumatoid arthritis were randomized to receive treatment with sequential monotherapy, step-up combination therapy, initial combination therapy with prednisone, or initial combination therapy with infliximab. The purpose of this study was to determine whether initial effects of these combination therapies were retained at a 2-year follow-up. Results at the 2 year follow up ...

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