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ACE Report #7849
Ace Report Cover Osteoarthritis

ISAKOS 2015: PRP has better pain and function at 6 months than HA in knee OA

Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A

HA vs PRP: Double-Blind RCT Comparing Clinical Outcomes and Intra-Articular Biology for Treatment of Knee Arthritis

Contributing Authors: BJ Cole LA Fortier V Karas K Hussey AK Tilton H Wilson DB Merkow A Stuckey NN Verma Bach BR Jr B Forsythe

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This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.


111 patients were randomized to receive either platelet-rich plasma (PRP) or hyaluronic acid (HA) in the treatment of knee osteoarthritis. The purpose of this study was to compare pain, function and biologic factors measured up to 6 months after treatment. Results found that PRP provided significantly greater improvements in pain and function over the 6 month period. Further assessments are needed...

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