Aprotinin reduces blood transfusion in patients undergoing total hip arthroplasty
Randomized Study of Aprotinin Effect on Transfusions and Blood Loss in Primary THAClin Orthop Relat Res. 2007 Dec;465:189-95
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393 patients undergoing elective primary total hip arthroplasty (THA) were randomized to receive aprotinin (a blood-conserving drug) or a placebo. The primary outcomes were the requirement for transfusions and blood loss. Results from this study indicated the use of aprotinin significantly reduces the requirement for blood transfusions when compared to a placebo treatment. No significant differenc...
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