AAOS 2015: Tranexamic acid effectively lowers blood loss following TKA without tourniquet
Tranexamic Acid Reduces Blood Loss in Patients Undergoing Knee Arthroplasty without Tourniquet
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50 patients undergoing unilateral total knee arthroplasty without a pneumatic tourniquet were randomized to receive tranexamic acid (TXA) perioperatively or placebo. The purpose of this study was to evaluate the safety and efficacy of TXA in patients being operated without a tourniquet, as compared to a placebo-controlled group. Total blood loss, rate of transfusion, and hematocrit and hemoglobin ...
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