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ACE Report #7642
Ace Report Cover Arthroplasty

AAOS 2015: Tranexamic acid effectively lowers blood loss following TKA without tourniquet


Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A

Tranexamic Acid Reduces Blood Loss in Patients Undergoing Knee Arthroplasty without Tourniquet

Contributing Authors: G Vindver F Bidolegui S Pereira A Lugones G Arce

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CONFERENCE ACE REPORTS

This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.

Synopsis

50 patients undergoing unilateral total knee arthroplasty without a pneumatic tourniquet were randomized to receive tranexamic acid (TXA) perioperatively or placebo. The purpose of this study was to evaluate the safety and efficacy of TXA in patients being operated without a tourniquet, as compared to a placebo-controlled group. Total blood loss, rate of transfusion, and hematocrit and hemoglobin ...

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