AAOS 2015: No difference between topical and intravenous tranexamic acid for TKA
The Effect of Topical Tranexamic Acid during Arthroplasty of the Knee on Blood Loss
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131 patients undergoing total knee arthroplasty were randomized to receive tranexamic acid either topically, with 2mg injected intra-articularly following capsular closure, or 1 mg intravenously prior to tourniquet inflation and another 1mg prior to tourniquet deflation. Postoperative hemoglobin levels and cumulative blood loss were assessed for 3 days postoperatively, and length of stay, discharg...
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