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Mesenchymal stem cell vs. chondrocyte implantation for repair of chondral knee defects

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Ace Report Cover
April 2015

Mesenchymal stem cell vs. chondrocyte implantation for repair of chondral knee defects

Vol: 4| Issue: 4| Number:83| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Matrix-induced autologous mesenchymal stem cell implantation versus matrix-induced autologous chondrocyte implantation in the treatment of chondral defects of the knee: a 2-year randomized study

Arch Orthop Trauma Surg. 2015 Feb;135(2):251-63.

Contributing Authors:
I Akgun MC Unlu OA Erdal T Ogut M Erturk E Ovali F Kantarci G Caliskan Y Akgun

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Synopsis

14 patients with isolated single full-thickness femoral condylar chondral defects of the knee (>2 cm-squared in area) qualifying for cartilage repair surgery were randomized to receive either matrix-induced autologous mesenchymal stem cell implantation (m-AMI), or matrix-induced autologous chondrocyte implantation (m-ACI). The purpose of this study was to evaluate and compare the objective and sub...

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