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ACE Report #7559
Ace Report Cover Osteoarthritis

Efficacy of pharmacological treatments for primary knee osteoarthritis - meta-analysis

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Comparative effectiveness of pharmacologic interventions for knee osteoarthritis: a systematic review and network meta-analysis

Ann Intern Med. 2015 Jan 6;162(1):46-54.

Contributing Authors: RR Bannuru CH Schmid DM Kent EE Vaysbrot JB Wong TE McAlindon

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137 randomized controlled trials, consisting of 33,243 patients, were included in this network meta-analysis. The aim of this study was to assess and compare the efficacy of current pharmacologic treatments for primary knee osteoarthritis. Treatments such as intra-articular corticosteroids, intra-articular hyaluronic acid, acetaminophen, naproxen, ibuprofen, diclofenac, and celecoxib and oral and ...

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