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Intra-articular TXA may reduce blood loss following unilateral TKA

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Ace Report Cover
April 2015

Intra-articular TXA may reduce blood loss following unilateral TKA

Vol: 4| Issue: 4| Number:43| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:1

The reduction in blood loss with intra-articular injection of tranexamic acid in unilateral total knee arthroplasty without operative drains: a randomized controlled trial

Eur J Orthop Surg Traumatol. 2015 Jan;25(1):135-9.

Contributing Authors:
Y Yang YM Lv PJ Ding J Li Z Ying-Ze

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Synopsis

80 patients scheduled for primary unilateral total knee arthroplasty were randomized to receive an intra-operative, intra-articular injection of either tranexamic acid (TXA) or saline solution. This was done to determine whether intra-articular TXA injections are safe and efficacious in the reduction of blood loss and need for blood transfusion following total knee arthroplasty. Volume of blood lo...

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