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Opioid use effective in reducing pain and improving function in OA patients

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Ace Report Cover
August 2013

Opioid use effective in reducing pain and improving function in OA patients

Vol: 2| Issue: 7| Number:163| ISSN#: 2564-2537
Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:N/A

Efficacy and safety of opioids for osteoarthritis: a meta-analysis of randomized controlled trials

Osteoarthritis Cartilage. 2007 Aug;15(8):957-65. Epub 2007 Mar 29

Contributing Authors:
J Avouac L Gossec M Dougados

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Synopsis

This meta-analysis identified 22 randomized controlled trials that compared the use of opioids to placebo or non-opioid analgesics with respect to the reduction of pain and improved function in patients with osteoarthritis. Of these studies, 18 were randomized placebo-controlled trials (the other 4 studies compared opioids to NSAID's or paracetamol, and did not provide enough robust data). Of the ...

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