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RCT
ACE Report #7456
Ace Report Cover Arthroplasty

Edoxaban has similar efficacy to enoxaparin for thromboprophylaxis after THA


Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Safety and efficacy of edoxaban, an oral factor xa inhibitor, for thromboprophylaxis after total hip arthroplasty in Japan and Taiwan

J Arthroplasty. 2014 Dec;29(12):2439-46.

Contributing Authors: T Fuji CJ Wang S Fujita Y Kawai T Kimura S Tachibana

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Synopsis

264 patients scheduled for total hip arthroplasty were randomized to one of three groups: a group which received 15mg edoxaban daily, a group which received 30mg edoxaban daily, or a group which received 20mg of enoxaparin sodium twice daily. This was done to determine the safety, efficacy, and optimal dosage regimen of edoxaban as compared to enoxaparin in patients undergoing total hip arthroplas...

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