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Long-term safety and effectiveness of tanezumab 10 mg vs. 20 mg for chronic low back pain

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Ace Report Cover
December 2016

Long-term safety and effectiveness of tanezumab 10 mg vs. 20 mg for chronic low back pain

Vol: 5| Issue: 12| Number:47| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Long-term safety and effectiveness of tanezumab as treatment for chronic low back pain

Pain. 2014 Sep;155(9):1793-801.

Contributing Authors:
JS Gimbel AJ Kivitz C Bramson MA Nemeth DS Keller MT Brown CR West KM Verburg

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Synopsis

849 patients with chronic low back pain (equal or > 3 months) were randomized to receive three intravenous injections of 10 mg or 20 mg of tanezumab followed by up to 4 subcutaneous injections every 8 weeks. This extension study aimed to compare the long-term safety and effectiveness of two different tanezumab doses. Ten and 20 mg doses of tanezumab produced similar effectiveness outcomes at 24 we...

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