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ACE Report #7066
Ace Report Cover Osteoarthritis

Knee OA - The therapeutic trajectory of corticosteroids and hyaluronic acid

Study Type:Meta-analysis/Systematic Review
OE Level Evidence:1
Journal Level of Evidence:N/A

Therapeutic trajectory of hyaluronic acid versus corticosteroids in the treatment of knee osteoarthritis: a systematic review and meta-analysis

Arthritis Rheum. 2009 Dec 15;61(12):1704-11

Contributing Authors: RR Bannuru NS Natov IE Obadan LL Price CH Schmid TE McAlindon

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7 randomized controlled trials (RCTs) were included in this systematic review and meta-analysis comparing conservative treatment methods of intra-articular hyaluronic acid injections and corticosteroid injections. Pain scores were pooled at 2, 4, 8, 12, and 26 weeks post-injection. At early follow-up (2 weeks), treatment with corticosteroid injections resulted in lower pain when compared to treatm...

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