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No difference between uniform and weighted dosing of TXA for hemostasis after TKA
November 2014
No difference between uniform and weighted dosing of TXA for hemostasis after TKA
Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:N/A
Weighted versus uniform dose of tranexamic acid in patients undergoing primary, elective knee arthroplasty: a prospective randomized controlled trial
J Arthroplasty. 2014 Sep;29(9 Suppl):186-8Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
44 patients undergoing total knee arthroplasty were randomized to a single uniform 1g dose of tranexamic acid or a single weighted 20mg/kg dose of tranexamic acid. The purpose was to determine if there was a difference between the two dosing regimens for reducing blood loss and transfusion requirements. Results demonstrated that there were no significant differences in intraoperative blood loss, p...
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