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Non-inferior efficacy of topical TXA to IV TXA in total knee arthroplasty patients

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Ace Report Cover
October 2014

Non-inferior efficacy of topical TXA to IV TXA in total knee arthroplasty patients

Vol: 3| Issue: 10| Number:37| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:1

Comparison of Intravenous versus Topical Tranexamic Acid in Total Knee Arthroplasty: A Prospective Randomized Study

J Arthroplasty. 2014 Aug;29(8):1528-31

Contributing Authors:
JN Patel JM Spanyer LS Smith J Huang MR Yakkanti AL Malkani

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Synopsis

89 patients undergoing unilateral total knee arthroplasty were randomly assigned to receive either topical Tranexamic Acid or Intravenous Tranexamic Acid. This study aimed to compare the efficacies of each route of administration on the reduction of blood loss following primary total knee arthroplasty. Results suggested no statistical difference in the perioperative change in hemoglobin levels bet...

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