Loading...
Visit our Evidence-Based Covid-19 Website and Stay Up to Date with the latest Research.
RCT
ACE Report #6705
Ace Report Cover General Orthopaedics

Extended-release metoprolol in the prevention of CV complications in non-cardiac surgery


Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial

Lancet. 2008 May 31;371(9627):1839-47. doi: 10.1016/S0140-6736(08)60601-7. Epub 2008 May 12.

Contributing Authors: POISE Study Group PJ Devereaux H Yang S Yusuf G Guyatt K Leslie JC Villar D Xavier S Chrolavicius L Greenspan J Pogue P Pais L Liu S Xu G Málaga A Avezum M Chan VM Montori M Jacka P Choi

Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here

Synopsis

9298 patients with, or at risk of, atherosclerotic disease and undergoing non-cardiac surgery, were randomized to receive perioperative administration of either extended-release metoprolol or a placebo equivalent. The purpose of this study was to compare these two groups with respect to rates of cardiovascular complications over a period of 30 postoperative days. Results indicated that, although t...

CME Image

Continuing Medical Education Credits

You could be earning 0.5 CME credits for each report you read.

LEARN MORE

Please Login or Join to leave comments.