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Meta-analysis
ACE Report #6646
Ace Report Cover Arthroplasty

TKA: LIA effective short term analgesia in terms of VAS, morphine consumption and function


Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:N/A

Efficacy and safety of single-dose local infiltration of analgesia in total knee arthroplasty: a meta-analysis of randomized controlled trials

Knee. 2014 Jun;21(3):636-46

Contributing Authors: CP Xu X Li ZZ Wang JQ Song B Yu

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Synopsis

Data from 18 RCTs, with 1858 patients who underwent total knee arthroplasty, were pooled to investigate the efficacy of local infiltration analgesia (LIA) against controls. Pooled analyses of VAS pain at 2, 4, 6, 12, 24, and 48 hours were conducted, along with morphine consumption, functional recovery, length of stay, and adverse events. The evidence presented in this meta-analysis demonstrated th...

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