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ACE Report #618
Ace Report Cover Osteoarthritis

Efficacy evaluation of highly purified intra-articular hyaluronic acid vs hylan G-F20


Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Efficacy evaluation of highly purified intra-articular hyaluronic acid (Sinovial(®)) vs hylan G-F20 (Synvisc(®)) in the treatment of symptomatic knee osteoarthritis. A double-blind, controlled, randomized, parallel-group non-inferiority study.

. 2011 ;():.

Contributing Authors: K Pavelka D Uebelhart

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Synopsis

381 patients with knee osteoarthritis (OA) were randomized to receive intra-articular injections with either Synovail (highly purified intra-articular hyaluronic acid) or Synvisc (hylan G-F20) once a week for three weeks. This double blinded randomized trial examined the efficacy and non-inferiority of Synovial treatment in patients with OA of the knee. The results from this study indicate that bo...

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