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TKA: Intra-articular tranexamic acid reduces blood loss and knee joint swelling

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Ace Report Cover
August 2013

TKA: Intra-articular tranexamic acid reduces blood loss and knee joint swelling

Vol: 2| Issue: 7| Number:129| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Intra-articular injection of tranexamic acid reduces not only blood loss but also knee joint swelling after total knee arthroplasty

Int Orthop; 2011; 35(11):1639-1645

Contributing Authors:
Kazunari Ishida Nobuhiro Tsumura Atsushi Kitagawa Sayaka Hamamura Koji Fukuda Yoshihiro Dogaki Seiji Kubo Tomoyuki Matsumoto Takehiko Matsushita Takaaki Chin Tetsuhiro Iguchi Masahiro Kurosaka andRyosuke Kuroda

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Synopsis

100 patients undergoing total knee arthroplasty (TKA) due to osteoarthritis were randomized to receive either an intra-articular injection of tranexamic acid (TXA) or saline (control). The post-operative results of the study indicated that the blood loss and subsequent drop in the hemoglobin levels were significantly reduced in patients that received TXA. Additionally, knee joint swelling was also...

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