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Volume:2 Issue:4 Number:26 ISSN#:2563-5476
Meta-analysis
ACE Report #5967
Ace Report Cover General Orthopaedics

Blood loss and transfusion needs reduced with TXA in major orthopaedic surgery


Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:N/A

The use of tranexamic acid to reduce blood loss and transfusion in major orthopedic surgery: a meta-analysis

J Surg Res. 2014 Jan;186(1):318-27. doi: 10.1016/j.jss.2013.08.020. Epub 2013 Sep 13

Contributing Authors: F Huang D Wu G Ma Z Yin Q Wang

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Synopsis

46 randomized controlled trials were included in this meta-analysis to investigate the use of tranexamic acid (TXA) in major orthopaedic surgery. The purpose of this analysis was to determine if blood loss and transfusion requirements were reduced with the application of TXA. Results revealed that intraoperative, postoperative and total blood loss were significantly reduced with tranexamic acid. T...

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