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Tranexamic Acid reduces blood loss and required transfusions in TKA patients
January 2014
Tranexamic Acid reduces blood loss and required transfusions in TKA patients
Study Type:Meta-analysis/Systematic Review
OE Level Evidence:2
Journal Level of Evidence:N/A
Topical tranexamic acid in total knee replacement: a systematic review and meta-analysis
Knee. 2013 Oct;20(5):300-9Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
7 studies were analyzed in this meta-analysis, (2 high quality randomized control trials (RCT), 3 lower quality RCTs (quasi-randomized/level of evidence 2), and one prospective case control), to determine the efficacy of topical tranexamic acid (TA) on blood loss following total knee arthroplasty. The pooled data of these trials revealed total drain output, total blood loss, and risk of transfusio...
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