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Volume:1 Issue:3 Number:122 ISSN#:2563-5476
ACE Report #552
Ace Report Cover Arthroplasty

Tranexamic Acid Reduces Blood Loss and Blood Transfusion after TKA

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Tranexamic acid reduces blood loss and blood transfusion after TKA: a prospective randomized controlled trial

Clin Orthop Relat Res. 2011 Oct;469(10):2874-80. Epub 2011 Apr 22

Contributing Authors: Keerati Charoencholvanich Pichet Siriwattanasakul

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100 patients with primary osteoarthritis who were scheduled to undergo unilateral cemented total knee arthroplasty were randomized to receive either placebo or intravenous tranexamic acid 10 minutes prior to surgery, 3 hours after surgery, and orally for 5 days after surgery. Patients who received tranexamic acid displayed significantly less blood loss, hemoglobin loss, and required significantly ...

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