Tranexamic Acid Reduces Blood Loss and Blood Transfusion after TKA
Tranexamic acid reduces blood loss and blood transfusion after TKA: a prospective randomized controlled trialClin Orthop Relat Res. 2011 Oct;469(10):2874-80. Epub 2011 Apr 22
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100 patients with primary osteoarthritis who were scheduled to undergo unilateral cemented total knee arthroplasty were randomized to receive either placebo or intravenous tranexamic acid 10 minutes prior to surgery, 3 hours after surgery, and orally for 5 days after surgery. Patients who received tranexamic acid displayed significantly less blood loss, hemoglobin loss, and required significantly ...
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