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Tanezumab effectively and safely reduces OA hip pain and improves physical function

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Ace Report Cover
October 2013

Tanezumab effectively and safely reduces OA hip pain and improves physical function

Vol: 2| Issue: 9| Number:14| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Tanezumab Reduces Osteoarthritic Hip Pain: Results of a Randomized, Double-Blind, Placebo-Controlled Phase III Trial

Arthritis Rheum. 2013 Jul;65(7):1795-803. doi: 10.1002/art.37950

Contributing Authors:
MT Brown FT Murphy DM Radin I Davignon MD Smith CR West

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Synopsis

627 patients with hip osteoarthritis (OA) were randomized to receive either 2.5 mg, 5 mg, or 10 mg doses of intravenous tanezumab (monoclonal antibody against nerve growth factor) or a placebo. The purpose was to compare each treatment's efficacy in lowering pain. After 32 weeks, results indicated that patients who were treated with tanezumab had significantly greater improvements in pain and phys...

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