The effect of rhBMP-2 in single-level posterior lumbar interbody arthrodesis

Study Type:Therapy

OE Level Evidence:2

Journal Level of Evidence:N/A

The effect of recombinant human bone morphogenetic protein-2 in single-level posterior lumbar interbody arthrodesis

J Bone Joint Surg Am. 2013 May 15;95(10):873-80. doi: 10.2106/JBJS.L.00137

Contributing Authors: J Michielsen J Sys A Rigaux C Bertrand

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Synopsis

40 patients undergoing single-level posterior lumbar interbody arthrodesis were randomized to receive two polyetheretherketone cages filled with either recombinant human bone morphogenetic protein-2 (rhBMP-2) or an autologous iliac crest bone graft. The purpose of the study was to determine whether there were any differences in clinical and radiographic outcomes between the two groups of patients....