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Volume:1 Issue:8 Number:89 ISSN#:2563-5476
RCT
ACE Report #481
Ace Report Cover Osteoarthritis

Effectiveness of Alendronate versus Alfacalcidol in maintaining bone mineral density


Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

A Comparison of the Effects of Alendronate and Alfacalcidol on Bone Mineral Density Around the Femoral Implant and in the Lumbar Spine After Total Hip Arthroplasty

Journal of Bone and Joint Surgery American; 2011; 93(A); 1203-1209

Contributing Authors: Naoyuki Iwamoto Yutaka Inaba Naomi Kobayashi Takashi Ishida Yohei Yukizawa Tomoyuki Saito

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Synopsis

60 elderly patients with osteoarthritis (OA),who had undergone cementless total hip arthroplasty, were randomized to receive either no drug treatment, alendronate, or alfacalcidol to determine the effects on bone mineral density (BMD). The results of the 48-week trial indicated that alendronate maintained BMD in all areas of the femur, whereas groups who received no treatment or alfacalcidol had p...

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