Annual infusion of zoledronic acid reduces days of back pain, disability, and bed rest
Once-yearly zoledronic acid and days of disability, bed rest, and back pain: randomized, controlled HORIZON Pivotal Fracture TrialJ Bone Miner Res. 2011 May;26(5):984-92. doi: 10.1002/jbmr.292
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In a secondary prespecified analysis, 7736 postmenopausal women with osteoporosis were examined to evaluate the effect of once-yearly zoledronic acid on improving back pain and disability. Patients received either a single 15 minute intravenous fusion of zoledronic acid (5 mg) or placebo at baseline, 12 months, and 24 months. The assessment at 36 months indicated that zoledronic acid significantly...
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