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Oral dabigatran as effective as enoxaparin in preventing thromboprophylaxis after THA
March 2014
Oral dabigatran as effective as enoxaparin in preventing thromboprophylaxis after THA
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Oral dabigatran versus enoxaparin for thromboprophylaxis after primary total hip arthroplasty (RE-NOVATE II*). A randomised, double-blind, non-inferiority trial
Thromb Haemost. 2011 Apr;105(4):721-9. doi: 10.1160/TH10-10-0679. Epub 2011 Jan 12Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
2055 patients undergoing total hip arthroplasty (THA) were randomized to receive oral dabigatran or subcutaneous enoxaparin to compare the impact each pharmaceutical had on the incidence of venous thromboembolism (VTE) and all-cause mortality. Following assessments over a 3 month period, the results displayed that both dabigatran and enoxaparin were equally effective in preventing VTE following TH...
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