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Ronacaleret does not significantly reduce time to healing of distal radius fracture
November 2013
Ronacaleret does not significantly reduce time to healing of distal radius fracture
Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:N/A
Ronacaleret, a calcium-sensing receptor antagonist, has no significant effect on radial fracture healing time: results of a randomized, double-blinded, placebo-controlled Phase II clinical trial
Bone. 2011 Oct;49(4):845-52. doi: 10.1016/j.bone.2011.06.017. Epub 2011 Jun 30Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
85 patients were randomized to determine the effect of orally administered ronacaleret, a calcium-sensing receptor antagonist, on distal radius fracture healing. Patients were prescribed either 200mg ronacaleret twice daily, 400mg ronacaleret once daily, or a placebo for 12 weeks. The results indicated neither ronacaleret regimen significantly reduced time to radiographic healing of the fracture, ...
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