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The effect of 3 versus 6 years of zoledronic acid treatment on femoral neck-BMD

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Ace Report Cover
July 2013

The effect of 3 versus 6 years of zoledronic acid treatment on femoral neck-BMD

Vol: 2| Issue: 6| Number:80| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

The effect of 3 versus 6 years of zoledronic acid treatment of osteoporosis: a randomized extension to the HORIZON-Pivotal Fracture Trial (PFT)

J Bone Miner Res. 2012 Feb;27(2):243-54. doi: 10.1002/jbmr.1494

Contributing Authors:
DM Black IR Reid S Boonen C Bucci-Rechtweg JA Cauley F Cosman SR Cummings TF Hue K Lippuner P Lakatos PC Leung Z Man RL Martinez M Tan ME Ruzycky G Su R Eastell

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Synopsis

This study was conducted to examine the long-term effects of zoledronic acid (ZOL) on bone mineral density (BMD) and fracture risk. 1233 postmenopausal women who received ZOL for 3 years in the previous study were randomized and received either 3 additional years of zoledronic acid or placebo. Results at 6 years revealed that between years 3 and 6, femoral neck-BMD remained constant in patients wh...

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