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Volume:2 Issue:4 Number:96 ISSN#:2563-5476
Author Verified
RCT
ACE Report #406
Ace Report Cover General Orthopaedics

Golimumab treatment provides superior treatment of rheumatoid arthritis


How to Cite

OrthoEvidence. Golimumab treatment provides superior treatment of rheumatoid arthritis . ACE Report. 2013;2(4):96. Available from: https://myorthoevidence.com/AceReport/Report/406

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Golimumab in patients with active rheumatoid arthritis after treatment with tumour necrosis factor alpha inhibitors (GO-AFTER study): A multicentre, randomised, double-blind, placebo-controlled, phase III trial

Lancet. 2009 Jul 18;374(9685):210-21. Epub 2009 Jun 26

Contributing Authors: JS Smolen J Kay MK Doyle R Landewé EL Matteson J Wollenhaupt N Gaylis FT Murphy JS Neal Y Zhou S Visvanathan EC Hsia MU Rahman GO-AFTER study investigators

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Synopsis

461 patients with rheumatoid arthritis who have undergone treatment with a TNF-alpha inhibitor previously were randomized to three groups. 2 groups were treated with either a 50 mg or 100 mg dosage of Golimumab and the third group received a placebo injection. The results indicated that treatment with Golimumab at either dose provided significant improvements in rheumatoid arthritis measures (ARC2...

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