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FREEDOM RCT follow-up: Denosumab does not delay fracture healing in osteoporosis patients
August 2013
FREEDOM RCT follow-up: Denosumab does not delay fracture healing in osteoporosis patients
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Denosumab Treatment in Postmenopausal Women with Osteoporosis Does Not Interfere with Fracture-Healing: Results from the FREEDOM Trial
J Bone Joint Surg Am. 2012 Oct 24. doi: 10.2106/JBJS.K.00774Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
7808 postmenopausal female patients with osteoporosis were randomized to receive 60 mg of denosumab or placebo every six months for 3 years. Over the course of the study, non-vertebral fractures occurred in 303 patients in the denosumab group (386 fractures) and 364 in the placebo group (465 fractures). 79 of the fractures in the denosumab group and 120 fractures in the placebo group were treated ...
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