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THR: Single pamidronate dose doesn't prevent development of osteolytic lesions

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Ace Report Cover
August 2013

THR: Single pamidronate dose doesn't prevent development of osteolytic lesions

Vol: 2| Issue: 7| Number:535| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Clinical and radiological outcome of total hip replacement five years after pamidronate therapy

J Bone Joint Surg Br. 2006 Oct;88(10):1309-15.

Contributing Authors:
N Shetty A J Hamer I Stockley R Eastell J M Wilkinson

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Synopsis

50 patients that underwent total hip replacements in 56 hips and were randomized to receive either a single intravenous infusion of pamidronate or a placebo to determine their effects of peri-prosthetic bone mineral density. After 5 years 37 patients (42 hips) returned for assessment. Throughout the course of the study the pamidronate group and placebo group achieved similar Harris hip scores and ...

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